THE ROLE OF SURGICAL TECHNOLOGIES IN THE TREATMENT OF VIRUS-ASSOCIATED TUMORS ON THE EXAMPLE OF HEPATOCELLULAR CARCINOMA
Authors: P.V. Balakhnin, A.S. Shmelev, E.G. Shachinov
Hepatocellular cancer (HCC) is the most difficult, but at the same time, the most interesting cancer from the point of view of surgical treatment of virus-associated tumor. In patients with virus-associated HCC, liver cirrhosis should be considered as a competing disease and this fact should be taken into account when determining treatment strategy. HCC is absolutely resistant to chemotherapy and radiation therapy (including stereotactic), therefore surgical (resection and liver transplantation) and IR (transarterial chemoembolization and percutaneous energy-based ablation) treatment methods are the only methods of effective therapy. In the past two decades, dramatic progress has been reached in the development of these technologies, which has significantly increased the survival of patients with very early, early and intermediate stages of HCC according to the BCLC classification.