Vaccination against hpv is the most effective of the known methods of primary prevention of malignant tumors

Human papilloma virus (HPV) causes cervical cancer, other anogenital tumors, and oropharyngeal cancer. Carcinogenic to humans are 14 types of HPV. Of these, two types of HPV 16 and HPV 18 account for 70% of cases of cervical cancer, more than 80% for anal cancer, 65% for vaginal cancer and 36% for vulvar cancer. To prevent infection with HPV and, accordingly, tumors caused by HPV, three vaccines have been created and recommended: two-, four- and nine-valent. The efficacy of these vaccines has been proven in randomized clinical trials. Ten years of experience in their application in practice has confirmed their very effectiveness. HPV vaccination is included in 98 countries’ national immunization schedules.