The journal «Practical oncology» / Т.18, №1 - 2017, The most important achievements in oncology in 2016
Repurposing drugs in oncology
Authors: D.B. Korman
Abstract:Drug repurposing (repositioning) is the process of developing new indications for existing drugs. The aim of repurposing drugs in oncology is applying existing,
well-characterized and well-used non-cancer drugs as agents in anticancer treatment. The present review summarized recent information about the anti-cancer effects and mechanisms of anti-cancer action for several drugs, commonly used for other medical indications (nitroglycerin, diclofenac, metformin, cimetidine, mebendazole).
Keywords: drug repurposing, oncology, nitroglycerin, diclofenac, metformin, cimetidine, mebendazole
