Urgent issues of drug therapy and possible solutions

Innovative diagnostic approaches and modern methods of treatment of malignant tumors have undoubtedly influenced the increase in life expectancy of patients, but so far have not led to the possibility of a complete cure of patients with disseminated forms of tumors. This article highlights the reasons that prevent metastatic and advanced cancer from becoming a curable disease. This publication demonstrates a critical understanding of the possibilities and disadvantages of precision oncology, represents a transitional stage in the current understanding of the place of immunotherapy in the treatment of disseminated patients, updates the place of standard chemotherapy in the era of immunotherapy and targeted therapy, concretizes the possibility of improving the results of treatment of common and metastatic forms of malignancies.