The journal «Practical oncology» / , The most important events in Oncology in 2019

Microbiome and its role in oncology



Microbiome is a now thought to be a unique isolated ecosystem, that tightly interact with host organism. Among functions that are influenced by microbiome we can mention energetic homeostasis, central nervous system functioning, activity of innate and diversity of adaptive immunity. As a consequence of such interaction the qualitative and quantitative composition of microbiome might influence many pathologic and physiologic processes, among which are malignant solid tumors. In this article we try to summarize up-to-date information on the role of microbiome in the appearance, clinical course and treatment of various solid tumors.